No wins in three and they just suffered a significant Champions League loss. Missing the injured Eden Hazard and Marco Asensio. Missing the suspended Rodrygo.
Ahead of this LaLiga match, Real Madrid were in Champions League action at home to Manchester City on Wednesday and lost that match 2-1.
That was their second loss in a row and before that they had a draw. So, the mood right now isn't great at Real Madrid.
Starting forward Eden Hazard had just returned from injury, but suffered a new ankle fracture at the weekend. He is ruled out for the foreseeable future.
Backup forward Marco Asensio is out injured and backup forward Rodrygo is suspended.
There is good depth at the forward positions for Real Madrid, though, and two of Vinicius, Lucas Vazquez, Gareth Bale and Isco can partner Karim Benzema up front.
Real Madrid will have had one less day of rest compared to Barcelona since their Champions League game was on Wednesday and Barcelona's Champions League game was on Tuesday.