James Pearson a long-term absentee otherwise head coach Daryl McMahon has a fully-fit squad for the visit from Crawley Town.
Macclesfield Town beat a Newcastle United B-team 2-1 in a midweek EFL Trophy group tie at the Moss Rose.
Daryl McMahon made ten changes to his starting line-up with Reice Charles-Cook named between the sticks.
Experienced trio David Fitzpatrick, Nathan Cameron and Michael Rose were handed recalls having been out of favour for league matches.
Eddie Clarke, Fraser Horsfall, Arthur Gnahoua, Connor Kirby, Jacob Blyth and Virgil Gomis were all given starting roles.
McMahon has no new injury concerns and is likely to revert to the same starting XI which drew 2-2 at Stevenage last weekend.
Miles Welch-Hayes and Jay Harris are both set to return after being rested in midweek.
James Pearson remains sidelined with a long-term knee injury.
The Silkmen will be hoping to EFL will approve a proposed loan move for Adi Yussuf from Blackpool.
Macclesfield Town won 2-0 when the two sides last met at the Moss Rose in December 2018.